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New preventive and societal medicine course 
UNMC's Department of Preventive and Societal Medicine will offer "PSM 835: Design of Medical Studies" in the Spring 2007 semester. The new course is worth three credits and is designed to prepare the student to understand and apply principles and methods in the design of biomedical and public health studies, with a particular emphasis on randomized, controlled clinical trials. The major design topics to be covered include sample selection, selecting a comparison group, eliminating bias, need for and processes of randomization, reducing variability, choosing endpoints, intent-to-treat analyses, sample size justification, adherence issues, longitudinal follow-up, interim monitoring, research ethics and non-inferiority and equivalence hypotheses. Data collection and measurement issues also will be discussed. Prerequisites include Biostatistics I, PSM806 or an equivalent, an introductory statistics course and instructor permission. The class will be on Mondays from 5:30 p.m. to 8:10 p.m. in Durham Research Center, room 1005. Contact Julie A. Stoner, Ph.D., associate professor in the biostatistics section of the department of preventive and societal medicine, at 559-7584 or at jstoner@unmc.edu for more information.

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