Target Audience

Nurse practitioners, advanced practice nurses, physician assistants, primary care providers, and other interested healthcare professionals.

Learning Outcomes

• Discuss evidence-based strategies for optimizing medication regimens, addressing medication non-adherence, and managing therapeutic challenges while considering patient-specific factors.
• Identify emerging trends in pharmaceutical research, highlighting their potential impact on future treatment modalities and healthcare delivery.
• Evaluate the pharmacokinetic and pharmacodynamic properties of medications used in diverse clinical scenarios, recognizing their mechanisms of action, metabolism, and/or potential interactions.

Method of Participation

The estimated time to complete each activity is listed.

• Read this front matter information
• Register for desired activities
• Click on the Course Materials tab
• Enter User ID and Password (issued after registering) and click "Login"
• Participate in the entire learning activity
• Complete the online evaluation for each activity
• Pass each post-test
• Upon successful completion of the post-test and evaluation, your certificate of completion will be available to print or save for each activity.

Disclosure Information

As a jointly accredited provider, the University of Nebraska Medical Center (UNMC) ensures accuracy, balance, objectivity, independence, and scientific rigor in its educational activities and is committed to protecting learners from promotion, marketing, and commercial bias. Faculty (authors, presenters, speakers) are encouraged to provide a balanced view of therapeutic options by utilizing either generic names or other options available when utilizing trade names to ensure impartiality.

All faculty, planners, and others in a position to control continuing education content participating in a UNMC accredited activity are required to disclose all financial relationships with ineligible companies. As defined by the Standards for Integrity and Independence in Accredited Continuing Education, ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. The accredited provider is responsible for mitigating relevant financial relationships in accredited continuing education. Disclosure of these commitments and/or relationships is included in these activity materials so that participants may formulate their own judgments in interpreting its content and evaluating its recommendations.

This activity may include presentations in which faculty may discuss off-label and/or investigational use of pharmaceuticals or instruments not yet FDA-approved. Participants should note that the use of products outside currently FDA-approved labeling should be considered experimental and are advised to consult current prescribing information for FDA-approved indications.

All materials are included with the permission of the faculty. The opinions expressed are those of the faculty and are not to be construed as those of UNMC.

DISCLOSURES

The accredited provider has mitigated and is disclosing identified relevant financial relationships for the following faculty, planners, and others in control of content prior to assuming their roles:

FACULTY
Anna Kohll, PharmD
Owner: Kohll's RX
Business Relationship: Organon Pharmaceuticals and Ferring Pharmaceuticals

The below faculty have nothing to disclose:

• Kenton Amstutz, DO, FAAP
• Bethany Berg, PA-C, MPAS
• Heather Chambers, DNP, FNP-C, APRN*
• Ardsley Congdon III, PharmD, BCPS, BCPP
• Rachel Cushing, DMSc, PA-C
• Joseph Fibich, PharmD
• Kelly Gassman, MPAS, PA-C, CAQ-Psych
• Kimberly Haynes-Henson, MD
• Christopher Shaffer, PharmD, PhD, MS
• Elizabeth Weedin, DO, MS, FACOG
• Erin Williams, MSN, ARPN, FNP-C
• Kenneth Zoucha, MD

*Faculty and planning committee member

PLANNING COMMITTEE

Margaret Emerson, DNP, APRN, PMHNP-BC
Advisory Board/Consultant: Otsuka

The below planning committee members have nothing to disclose:

• Rita Antonson, MSN, APRN, GNP-BC
• Claire Beweja, DNP, APRN, FNP-C, CEN, SANE-A
• Lois Dauel, APRN, BSN
• Teri Diederich, DNP, CHFN, FHFSA
• Wende Heckert, DNP, APRN-NP
• LeAnn Holmes, DNP, APRN, FAANP
• Heidi Keeler, PhD, MSN/MBA, RN
• Kathy Murphy-Buschkoetter, DNP, APRN, FNP-BC
• Renee Paulin, MSN, RN, CWOCN
• Courtney Smith, MBA
• Kathleen Yao, DNP, APRN-NP, WHNP-BC

OFF-LABEL DISCLOSURES

• Ardsley Congdon III, PharmD, BCPS, BCPP
  • Sublocade and Brixadi: Drug brands with buprenorphine administered via injection
• Kelly Gassman, MPAS, PA-C, CAQ-Psych
  • Buprenorphine: Alternative dosing regimens
  • Naltrexone: Use for non-opioid or alcohol substances
• Kimberly Haynes-Henson, MD
  • Pain Medications: Anti-seizure and Anti-depressant
• Anna Kohll, PharmD
  • Human growth hormone used for egg quality and quantity impact
• Kenneth Zoucha, MD
  • Naltrexone, Bupropion, Nicotine Replacement: Drugs used in adolescents under 18 years of age

ACCREDITED CONTINUING EDUCATION

				In support of improving patient care, University of Nebraska Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. The University of Nebraska Medical Center designates this activity for up to 12.0 ANCC contact hours. Nurses should only claim credit for the actual time spent participating in the activity. Up to 12.0 contact hours are related to pharmacotherapeutic content.
				University of Nebraska Medical Center has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for up to 12.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.